Asprin May Cut Some Cancer Deaths in Women
Older women who take non-steroidal anti-inflammatory drugs -- such as aspirin or ibuprofen -- appear to have a lower risk of death from colorectal cancer than women who don't use these medications, a large new study suggests.
Women who reported using these drugs, called NSAIDs, at the beginning of the study and three years later had a roughly 30 percent lower rate of death from colorectal cancer than women who did not take the drugs, or women who took them at only one of these two points in time, according to the American Association for Cancer Research (AACR).
"Our results suggest that non-steroidal anti-inflammatory drug use is associated with lower colorectal cancer mortality among postmenopausal women who use these medications more consistently and for longer periods of time," says Anna Coghill, a doctoral student in epidemiology at the University of Washington and Fred Hutchinson Cancer Research Center.
In the study, researchers examined the use of aspirin and non-aspirin NSAIDs among more than 160,000 postmenopausal women in relation to deaths from colorectal cancer.
Study participants were enrolled in the Women's Health Initiative, which "represents a large and well-characterized cohort of postmenopausal women, and the medication data collected in this cohort made it possible for us to investigate multiple types, durations and strengths of NSAID use," Coghill says.
The researchers confirmed 2,119 cases of colorectal cancer and 492 deaths due to the disease.
"The results of our study help to further clarify the importance of different durations of NSAID use over time for the risk for dying from colorectal cancer," Coghill says.
While the study found an association between NSAID use and a reduced risk of colorectal cancer, it did not prove a cause-and-effect.
The findings were slated for presentation on Sunday at the AACR International Conference on Frontiers in Cancer Prevention Research in Boston.
Experts say that for studies presented at medical meetings, data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.
More information: The U.S. National Cancer Institute has more about colon and rectal cancer.
© 2011 HealthDay
Comments:
There seems to be some info missing from this article. Most colorectal tumors are extremely slow growing (10+ years to become problematic), so it's puzzling to see how a study that lasted only 3 years would be very useful. We would also need to know how many, if any, of these women had colonoscopies. With proper screening at appropriate intervals, colon cancer is one of the few cancers that can usually be prevented.